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Perfection Peptide P3
Mibelle AG Biochemistry
The skin's own permanent exfoliation
renders the skin smooth and soft
Desquamation is the natural exfoliation process of our
skin. New keratinocytes are constantly formed in the basal layer of the
epidermis. From there cells migrate and differentiate to form the
outermost layer of the epidermis, the stratum corneum. At the surface,
dead cells are continuously shedded – the skin remains smooth, soft and
evenly toned.

In aged skin natural exfoliation process slows
down
As skin ages keratinocytes stick together stronger and
the desquamation process becomes slow and irregular. The skin gets dry,
rough, patchy and scaly and more and more uneven and its colour turns
dull and greyish.
PerfectionPeptide P3 rejuvenates by biomimetic
peelīng
Connection of cells is realized by desmosomes.
Desmocollin and desmoglein, proteins of desmosomes, bind together at
specific sites. PerfectionPeptide P3 contains a tripeptide that consists
of the three central amino acid residues of the binding sequence of one
of these proteins. Once PerfectionPeptide P3 is applied it impairs the
binding of adjacents cells. As a consequence, cells in the stratum
corneum lose contact possibilities with neighbouring cells and start to
peel off.
PerfectionPeptide P3 leads to a gentle peeling
For an optimal penetration PerfectionPeptide P3 is
encapsulated into liposomes. PerfectionPeptide P3 stimulates the natural
desquamation process of the skin leading to a gentle biomimetic peeling.
Consequently a brighter, smoother and even toned skin complexion is
created. Your skin is
rejuvenated and appears younger.
PerfectionPeptide P3 for smooth and even skin
A cream containing 1% PerfectionPeptide
P3 was applied for 17 days. Then the skin surface was analyzed with
scanning electron microscopy.
A rough skin surface is characterized by eruptive layers and a broad
distance between layers as seen at the left side. The skin treated with
PerfectionPeptide P3 clearly showed a smoother surface at the end of the
study (figure on the right).
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